Coagulation Cascade
coagulation cascade Triggered by the exposure of tissue factor in the damaged blood vessel wall to the circulating factor VII Final Common Pathway The Coagulation Cascade – Secondary Hemostasis- Coagulation cascade activation leading to stable Clot formation Page 4 Page 5 Page 6 Page 7 • I (fibrinogen • II
The classic coagulation cascade is divided into the extrinsic and intrinsic pathways which both The coagulation cascade is useful to understand as it provides a framework for interpreting basic coagulation tests -the PT and APTT
In circulation, CTCs imcrease degradative autophagy as a survival mechanism and can promote thrombogenesis through activation of the coagulation cascade on The concept of a coagulation cascade describes the biochemical interactions of the coagulation factors, but it is flawed as a model of the in vivo hemostatic